POTENSI JUS UMBI BIT SEBAGAI SUPLEMENTASI ANEMIA
Abstract
POTENTIAL OF BEETROOT JUICE AS ANEMIA SUPLEMENTATION
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Abstrak
Kebutuhan zat besi pada kehamilan secara signifikan terus meningkat sejalan dengan bertambahnya usia kehamilan. Sebanyak 48.9% ibu hamil di Indonesia mengalami anemia defisiensi besi. Stress oksidatif berkontribusi terhadap kejadian anemia defisiensi besi Zat besi sebagai pengobatan utama anemia defisiensi besi diketahui ikut serta dalam peningkatan radikal bebas melalui reaksi Fenton and Haber–Weiss. Tujuan penelitian ini adalah menginvestigasi kadar antioksidan GPx pada tikus bunting anemia yang diberi suplementasi jus umbi bit dan zat besi. Penelitian ini adalah penelitian eksperimental dengan desain Randomized Posttest Only Control Group Design. Hasil penelitian dianalisis dengan uji ANOVA One Way. Subjek penelitian terbagi dalam 5 kelompok pengamatan. Hasil penelitian ini adalah jus umbi bit dosis 3.6 gr/BB memiliki kemampuan yang lebih baik untuk mencapai kadar Glutation Peroksidase (GPx) sesuai dengan kelompok tikus sehat dibandingkan suplementasi zat besi 1.08 mg/BB. Kesimpulan peneltian inin adalah jus umbi bit terbukti berpotensi lebih baik untuk menyeimbangkan antioksidan pada penderita anemia defisiensi besi.
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Kata Kunci : Bit (Bet vularis L), Antioksidan, Glutation Peroksidase (GPx), Suplemetasi zat besi.
Keywords
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Bothwell, TH. 2000. Iron Requirements In Pregnancy And Strategies To Meet Them. Americal Journal Clinical Nutrition; 72: 257S–264S.
Viteri FE, Casanueva E, Tolentino MC, DÃaz-Francés J, Erazo AB. Antenatal iron supplements consumed daily produce oxidative stress in contrast to weekly supplementation in Mexican non-anemic women. Reprod Toxicol [Internet]. 2012;34(1):125–32. Available from: http://dx.doi.org/10.1016/j.reprotox.2012.03.010
Mei, Z. Serdula, MK. Liu, JM. Ayala, RCF. Wang, LL. Ye, R and Strawn, LMG. Iron-Containing Micronutrient Supplementation of Chinese Women with No or Mild Anemia during Pregnancy Improved Iron Status but Did Not Affect Perinatal Anemia. The Journal of Nutrition Nutritional Epidemiology. April 17, 2014; doi:10.3945/jn.113.189894.
Madhikarmi, LM and Murthy, KRS. Antioxidant Enzymes and Oxidative Stress in the Erythrocytes of Iron Deficiency Anemic Patients Supplemented with Vitamins. Iranian Biomedical Journal 18 (2): 82-87 (April 2014) DOI: 10.6091/ibj.1228.2013.
Patel, M. and Ramavataram, DVSS. 2012. Non Transferrin Bound Iron: Nature, Manifestations and Analytical Approaches for Estimation. Indian Journal Clinical Biochem 27(4):322–332.
Knutson, MD. Walter, PB. Ames, BN. Viteri, FE. 2000. Both Iron Deficiency and Daily Iron Supplements Increase Lipid Peroxidation in Rats. American Society for Nutritional Sciences.
Zhuang, T. Han, H Yang, Z. Iron, Oxidative Stress and Gestational Diabetes. Nutrients 2014, 6, 3968-3980; doi:10.3390/nu6093968. ISSN 2072-6643 www.mdpi.com/journal/nutrients
Lobo, V. Patil, A. Phatak, A. Chandra, N. 2010. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Review. Jul-Dec; 4(8): 118–126.
Indhumathi, T., & Kannikaparameswari K. Hematop Study Methanolic Root Extr Beta Vulgaris Albino Rats-an Vivo Study. International Journal of Pharma and Bio Sciences 2012;3(4):1005–15.
Rauha, JP. Remes, S. Heinonen, M. Hopia, A. Kähkönen, M. Kujala, T. Pihlaja, K. Vuorela, H. Vuorela, P. (2005). Antimicrobial effects of Finnish plant extracts containing flavonoids and other phenolic compounds. Int. J. Food Microbiol. 56: 3-12.
Okinarum, OY dan Zakiyah, Z. 2019. Pemanfaatan Herbal dalam Kebidanan. Pustaka Panasea: Yogyakarta.
Kanner, J., Harel, S., Granit, R., 2001, Betalains - A New Class Of Dietary Cationized Antioxidants. Journal of Agriculture and Food Chemistry, 49, 5178-5185.
Stintzing, F. C., Herbach, K. M., Mosshammer, M. R., Carle, R., Yi, W., Sellappan, S., Akoh, C. C., Bunch, R., Felker, P., 2005, Colour, Betalain Pattern, And Antioxidant Properties Of Cactus Pear (Opuntia spp.) Clones. Journal of Agriculture and Food Chemistry, 53, 442- 451.
Kapadia GJ, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines. Anticancer Agents Med Chem 2011;11:280-4.
Vulic JJ, Cebovic TN, Canadanovic VM, Cetkovic GS, Djilas SM, Canadanovic-Brunet JM, et al. Antiradical, antimicrobial and cytotoxic activities of commercial beetroot pomace. Food Funct 2013;4:713-21.
Jaiswal A, Ganeshpurkar A, Awasthi A, Bansal D, Dubey N. Protective effects of beetroot extract against phenyl hydrazine induced anemia in rats. Pharmacogn J. 2014;6(5):1–4.
Clifford,T. Howatson, G. West, DJ and Stevenson, EJ. The Potential Benefits of Red Beetroot Supplementation in Health and Disease Nutrients 2015, 7, 2801-2822; doi:10.3390/nu7042801. ISSN 2072 6643 www.mdpi.com/journal/nutrients
AL – Lamki, KNH. Ramli, MDC. Khun, YMK and Yusoff, MJ. Antioxidant Property of Beetroot Juice Stimulates Erythrocyte Antioxidant Enzymatic Activity under Oxidative Stress Stimulation. Vol. 15 No. 2 Dec, 2017 | Journal of Management and Science
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